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 Supportive wife comforting husband with TRD during a meeting with a counselor in Yorktown Heights.

What Is Treatment-Resistant Depression?

March 08, 2024

Once you’re found to have a depressive disorder, you look to treatments to help you alleviate symptoms like anxiety, desperation, and tiredness. Yet, what do you do if traditional antidepressants fail to offer relief or make your condition more unpleasant? If you have previously tried multiple treatments and still deal with depression, you could have Treatment-Resistant Depression (TRD). Find more details about this disorder and see if you or someone close to you could have Treatment-Resistant Depression.

How Are People Diagnosed With Treatment-Resistant Depression In Yorktown Heights?

Treatment-resistant depression describes individuals with major depressive disorder (MDD) who have taken two or more oral antidepressants to the prescribed dose and duration without a reduction of symptoms. Even though you might experience brief improvements in mood, they are most often succeeded by a return of symptoms. You may even realize that your episodes of depression are more prolonged and intense.

If antidepressants don’t work for you, you’re not alone. According to one study, between 29% and 46% of those who participated didn’t get extended relief from oral antidepressants.

What Are Treatment-resistant depression symptoms?

TRD is a subset of a Major Depressive Disorder. Consequently, the symptoms of treatment-resistant depression are known, but you are unable to get relief from usual antidepressants. These symptoms may include:

  • Continuing hopelessness or sadness
  • Loss of interest or delight in activities
  • Shifts in weight or appetite
  • Sleep issues like lethargy or insomnia
  • Detrimental thoughts about oneself.
  • Difficulty paying attention
  • Physical phantom pain in joints
  • Self-harm
  • Recurrent thoughts of death or suicide

It's important to understand that the frequency and intensity of these symptoms, regardless of treatment, make TRD distinctive from other forms of depression. In addition, managing TRD usually demands a more multi-faceted kind of depression treatment near Yorktown Heights, potentially including a mix of medications and therapy.

SPRAVATO Approved For Treatment-Resistant Depression

SPRAVATO is the first FDA-approved nasal spray to treat people 18 or older with treatment-resistant depression. Esketamine is the active pharmaceutical ingredient and is considered to mitigate symptoms by influencing certain pathways in the brain. In a clinical trial, people who were administered Spravato and an oral antidepressant enjoyed a greater reduction in depressive symptoms after four weeks than participants who were administered a placebo and an antidepressant.

SPRAVATO is given under the supervision of medical practitioners at a facility authorized by the Risk Evaluation and Mitigation Strategy (REMS) program. A comprehensive evaluation of your medical background is mandatory before use. Serious side effects can arise, including dissociation and sedation, and patients have to be monitored for two hours post treatment.

Contact The Counseling Center At Yorktown Heights For Help With Treatment-resistant Depression in Yorktown Heights

Treatment-resistant depression may bring about a new layer of anxiety with feelings that your condition might not get better. Thankfully, a new combination of medication, therapy, and professional care will help you get past TRD. The Counseling Center At Yorktown Heights is here to help. We provide a range of mental health services for treatment-resistant depression and are a certified SPRAVATO treatment center. Find help now by dialing 914-977-0608 or using the simple form on this page.